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D Leroith Selected Research

Oral Administration

6/2015The phosphorylated prodrug FTY720 is a histone deacetylase inhibitor that reactivates ERĪ± expression and enhances hormonal therapy for breast cancer.

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D Leroith Research Topics

Disease

2Insulin Resistance
07/2009 - 01/2006
2Type 2 Diabetes Mellitus (MODY)
07/2009 - 01/2006
1Carcinoma (Carcinomatosis)
06/2015
1Triple Negative Breast Neoplasms
06/2015
1Breast Neoplasms (Breast Cancer)
06/2015
1Multiple Sclerosis
06/2015
1Dyslipidemias (Dyslipidemia)
06/2008
1Abdominal Obesity
06/2008
1Hypertension (High Blood Pressure)
06/2008
1Metabolic Syndrome (Dysmetabolic Syndrome X)
06/2008
1Hyperplasia
01/2006
1Hypertrophy
01/2006

Drug/Important Bio-Agent (IBA)

3Glucose (Dextrose)FDA LinkGeneric
07/2009 - 01/2006
2Insulin (Novolin)FDA Link
07/2009 - 01/2006
1Estrogens (Estrogen)FDA Link
06/2015
1Fingolimod Hydrochloride (FTY720)FDA Link
06/2015
1ProdrugsIBA
06/2015
1Estrogen ReceptorsIBA
06/2015
1Progesterone Receptors (Progesterone Receptor)IBA
06/2015
1SphingosineIBA
06/2015
1TamoxifenFDA LinkGeneric
06/2015
1Histone Deacetylase InhibitorsIBA
06/2015
1sphingosine kinaseIBA
06/2015
1Lipoproteins (Lipoprotein)IBA
07/2009
1ApolipoproteinsIBA
07/2009
1Apolipoproteins E (ApoE)IBA
07/2009
1Blood Glucose (Blood Sugar)IBA
07/2009
1LipidsIBA
07/2009
1IGF Type 1 Receptor (IGF 1 Receptor)IBA
01/2006

Therapy/Procedure

1Oral Administration
06/2015
1Therapeutics
06/2015